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Impact of adherence to antiepileptic medications on quality of life of epileptic patients in the Eastern Province of Saudi Arabia: A cross-sectional study
Faheem Hyder Pottoo, Dhfer Mahdi Alshayban, Royes Joseph, Fatimah Al-Musa, Ola Al-Jabran, Danah Aljaafari
January-June 2020, 5(1):1-8
Epilepsy is one of the most common neurological diseases, characterized by recurrent epileptic seizures. Adherence to antiepileptic drugs (AEDs) is vital in establishing seizure control. The adherence, in turn, impacts the quality of life (QoL) in epileptic patients.
This was a hospital-based cross-sectional study conducted at King Fahd Hospital of the University, Qatif Central Hospital, and Dammam Central Hospital in the Eastern region of Saudi Arabia during the period from January 2018 to April 2018. Epileptic patients from all age groups treated with at least single AED and who had follow-up in hospital for the past 6 months were included in the study. Patients with intellectual disabilities and those who received AEDs for other indications were excluded. The participants were interviewed in Arabic, and validated translated version of questionnaire was completed under the following sections: sociodemographic characteristics, adherence assessment using the General Medication Adherence Scale (GMAS), and QoL in epilepsy patients using EQ-5D-5L.
We report 48% of participants with high adherence, 34% with moderate adherence, while 19% exhibited low adherence toward AEDs. Of 80 participants, 25 (31%) reported perfect health status (11,111) and 2 (3%) reported extremely worst health status (55,555). Further, the study revealed a significant (
= 0.045 and 0.035) improvement of QOL in patients with moderate and high adherence compared to patients with low adherence.
This study reports high health-related quality index (QoL) in participants with moderate–high adherence. The relationship between adherence and overall HRQoL was directly proportional.
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Awareness on the association between skin aging and smoking: Impact on smoking quitting
Arwa Z Fatani, Hussein M Alshamrani, Khalid A Alshehri, Abdullah Y Almaghrabi, Yahya A Alzahrani, Mohammed H Abduljabbar
January-June 2020, 5(1):33-37
This study aims to evaluate the public's knowledge and awareness of the association between cigarette smoking and skin aging in Jeddah, Saudi Arabia.
This is a cross-sectional study conducted by distributing a questionnaire to the general population of Jeddah across different age groups in 2018. Data were organized using a frequency distribution table, and analysis was done using Chi-square test.
Among 2443 participants, 68.2% were female and 12.6% were current smokers. More than half (64%) of the participants answered correctly that smoking increases facial aging. Slightly higher number of nonsmokers responded correctly than current and former smokers. There was a statistically significant difference between gender and the response to the association of smoking and skin aging, with majority of the females (71%) responding correctly (
< 0.0001). A considerable number of younger participants and college graduates knew that smoking increases wrinkles. Among the current smokers, 25% said that most/some smokers would quit if they learned that smoking increases facial aging. However, among the current smokers, there was no statistically significant association between their awareness of the relationship between smoking and skin aging and their motivation to quit (
The society's lack of knowledge about the association between cigarette smoking and skin aging needs more attention. Knowledge needs to be spread by prompting health campaigns and by the participation of health authorities to make more effective public health policies against smoking.
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